MEDICAL ANIMATION TRANSCRIPT: An injury to the skin, such as a cut, scrape, or puncture wound kills nearby cells and damages underlying structures and triggers the complex process of repairing the skin. Wound healing is a three-step process. The inflammatory phase begins immediately upon injury. Blood vessels constrict to reduce blood loss. Then, platelets arrive to plug the leak. The platelet plug initiates the clotting mechanism by facilitating the reactions of plasma proteins called clotting factors, which interact to form a fibrin clot. After the clot forms, the blood vessels vasodilate and become more porous to allow white blood cells to leave the blood vessel and populate at the site of injury. During this process called phagocytosis, white blood cells eat debris and kill bacteria, reducing the risk of infection. The proliferative phase begins two days to three weeks after injury. The first step in the proliferative stage is granulation. Connective tissue cells, called fibroblasts, lay a matrix of collagen that reinforces the wound and provides structure for other cells. Collagen then contracts to pull together the margins of the wound. Angiogenesis, or the growth of new blood vessels, begins almost simultaneously and supplies oxygen to the repairing cells. Epithelialization is the restoration of the protective skin barrier. Epithelial cells migrate from the margins of the wound, protected by the scab, until they meet. Eventually, the scab falls off. The remodeling phase begins several weeks after the injury and can continue for years. During this phase, a new, more organized collagen matrix forms in the wound bed and capillaries disappear, leaving an avascular scar. One possible complication of wound healing is keloid formation. A keloid results from an overgrowth of granulation tissue extending beyond the borders of the original wound. Composed of mostly collagen, keloids are slow-growing. They do not regress spontaneously, and tend to reoccur after excision. A common initial treatment for keloids includes multiple injections of corticosteroids to help reduce the size of the scar. ♪ [music] ♪
#WoundHealing #phagocytosis #epithelialization
ANM11023
39 Comments
Am I Wolverine!?
Allahu Ahkbar 😮😮😮
im pretty sure blood doesnt look like that
Scraped my leg and it's still bleeding almost a week later, not even close to being done.
i would love to know how this works with hemophilia
My body does this every day. I suck at shaving.
Sh twt where u at?
Down-voted for robovoice.
The human body is amazing 💕
Be a ginger is like be a vampire we heal faster from base cute in less time then none ginger will Iam a ginger and I sure do heal fast so it show
Understanding our bodies.
Me here because I accidentally cut my hand deeply while trying to open a can
How amazing is God's intelligent design?
We search for aliens but probably we are when you realize how complex machine is the human body
GOD IS REAL
I am here after i had a bike accident. I am.scared to go to the clinic because i have phobia. I.just clean my wounds on my knee and elbow by using hydroperoxide and wound cream.
Watching this video not long after I got a painful cut made it hurt more ngl
'No one loves me.'
Cells: Seriously?
Our bodies are incredible! It's too bad we abuse it 😢. I know I have unintentionally with my diet.😅
lets be honest, we all got a cut or a scrap so we searched this up curious
Beautiful video..
With all of that amazing systems and creation, people still don’t believe in God! Thanks to Allah to be Muslim
What about stitches
I have a pretty thick scab on my knee healing the cut right now, it’s so itchy but I try to peel the parts that are done healing so it doesn’t itch anymore, it works surprisingly well.
My body must be tired of my brain telling it to rip off all the scabs and start the healing process all over again. 😭
We low key wolverine Fr with this healing factor
Came to this video cause I kicked into filet knife above my big toe ts hurt
2:47 what's going on under the skin layer there?
Thats a whole medical procedure done by itself ,truly there is something out there who designed us who i call god
I saw what you did there in the thumbnail 😏
"We have a hull breach on deck 710, starboard leg. Constricting blood vessels to reduce venting. Security teams, repair teams, deploy. Lock it down! Diverting magnesium reserves!"
I feel bad for those little guys doing all that work just bc I’m addicted 😭
i recently accidentally cut my self with a kitchen knife and the cut was a bit deep. so i watched this video just to see how the cells would heal it🥹
No wonder woman menstruates because the blood needs to cover dem hole
I like this
I miss the clotting cascade
It's insane to think that evolution just figured this stuff out on its own, like what?!
LOBILLOS MUSICAL DE DURANGO…
OCT 27, 2K24…
09:30 PM
Very informative ty